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Turnover and degradation Biochemical studies of glutathione degradation in tobacco conducted by the Rennenberg group (Rennenberg, Steinkamp & Kesselmeier 1981

A major strength of this study is the extensive metabolic profiling of tissue-specific IR in both the fasting and the postprandial state, thereby broadening and deepening the characterization of plasma lipid profiles in tissue-specific IR and providing more insights into the metabolic abnormalities that are related to muscle or liver IR

More specifically, epidermal sphingolipids have been shown to be altered only in aged female skin [90], an effect that can be reversed by HRT [91, 92]