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Phase II human trials of thymosin beta-4 (TB-500's parent molecule) have been conducted examining tissue repair rates, with studies reporting acceleration of repair in patients with pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds, though detailed results remain limited in peer-reviewed literature

It also helps shrink large pores, dissolves blackheads, and removes dead skin cells for a refreshed and rejuvenated complexion

Topical application is considered very safe and well-tolerated, with no known adverse effects

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CRL4(DCAF2) negatively regulates IL-23 production in dendritic cells and limits the development of psoriasis