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Increase in bloodbrain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury

However, this physiological adaptation does not result in hypercholesterolemia

: "Improved ROS defense in the swimbladder of a facultative air-breathing erythrinid fish, jeju, compared to a non-air-breathing close relative, traira." in: Journal of comparative physiology

These cells are macrophage-like cells and are involved in the brains innate immune system, whose defense mechanisms are altered in neurodegenerative diseases such as AD (26)

Reduced glutathione (GSH) has shown slightly better results than oxidized forms (GSSG) in some studies