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Interestingly, the PEN HNF4A + /FGB + cells did not co-express PDX1, which suggests liver-like cell fate specification

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In a mouse model with I/R injury, the combination of cyclosporine A (CsA) and DFX synergistically inhibits I/R-induced iron overload, lipid peroxidation, and cardiomyocyte ferroptosis, reducing infarct size and improving poor cardiac remodeling after I/R injury

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