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Reference Ma, Kaundun, Tranel, Riggins, McGinness, Hager, Hawkes, McIndoe and Riechers2013) by the addition of NBD-Cl

In the presence of sufficient GSH, ROS and RNS can be curtailed to permit orderly formation of S-nitrosoGSH, a long lasting, diffusible NO donor that would be available and in close, intracellular proximity to the NO-sensitive hydroxyl of Tyr-274 of pox virus DNA topoisomerase