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Pentose Phosphate Pathway: Oxidative Phase The overall reaction of the oxidative phase of the pentose phosphate pathway is shown below: Glucose 6-phosphate + 2 NADP+ + H2O Ribulose 5-phosphate + 2 NADPH + 2 H+ + CO2 In the first step of the oxidative phase, glucose 6-phosphate is oxidized to 6-phosphoglucono--lactone, which is a lactone or cyclic ester (Figure 1)

Padil, M

We hypothesize that inhibiting intracellular glutamine transport via ASCT2, such as with V-9302, may be a more effective strategy for targeting glutamine metabolism in PIK3CA -mutant cancer cells than targeting downstream enzymatic activities, such as GLS1 or glutamine synthetase

Warnings Pregnancy This medicine is not recommended for use in pregnant women unless necessary

Sharma A, Sharma A, Tripathi A (2021) Biological activities of Pleurotus spp