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10.1097/j.pain.0000000000001514 84 FurukawaT.ItoK.NukaS.HashimotoJ.TakeiH.TakaharaM.et al (2009)

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Furthermore, it has emerged that supporting or inducing mitochondrial bioenergetics, stress responses, mitophagy, and other adaptation mechanisms is critical to mediate some of the health or longevity benefits observed in studies using NAD + modulation strategies

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