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This interference can lead to altered mitochondrial morphology and function, which are the primary sources of ROS in cells (Zhou et al., 2020)

The concomitant depletion of tryptophan and kynurenine may indicate impaired neuroprotective mechanisms or increased oxidative stress, aligning with the altered tryptophan metabolism observed with both NMR and UPLC/MS (Supplementary Figs

Heart Rhythm 19(2):235243 Zhou X, Fang X, Ithychanda SS, Wu T, Gu Y, Chen C, Wang L, Bogomolovas J, Qin J, Chen J (2023) Interaction of filamin C with actin is essential for cardiac development and function

The treatment plates included NGM + 0.5 % (v/v) DMSO (vehicle control, Ctl), NGM + 250 M SIH, and NGM + 200 M Lip-1 (as described above)

Nanotheranostics Development of theranostic platforms to investigate and modulate neuroinflammatory and neurodegenerative processes occurring during neurodegenerative disease progression, such as in AD, represents quite a novel and appealing strategy holding tremendous potential