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922 This process is necessary for the treatment resistance of AKT-hyperactivated cancer cells

DOI:10.2217/bmm-2021-0108 7

Theor Appl Genet 133:12011212

However, with regular IV sessions, these effects can be sustained for a period of weeks to months at a time

The resulting oxidized form of GSH either reacts with another GSH molecule to form GSSG or with cysteine groups on cellular proteins to form protein GSH mixed disulfides, a process known as protein glutathionylation. This latter reaction can change the proteins structure and function, which can, in turn, evoke a functional change within the cell