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Reactive oxygen species (ROS) are reported to be involved in different cellular processes ranging from apoptosis and necrosis to cell proliferation and carcinogenesis

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5 Antioxidative defence system in plants As mentioned, ROS are usually produced as typical by-products in plant metabolic processes like the ETC in mitochondria [146]

Furthermore, 2-ME2 treatment decreases transendothelial migration of hypoxiareoxygenation-exposed neutrophils in vitro, reduces TNF production, and enhances apoptosis [110]