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Clinical Trials Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer

10.1093/eurheartj/ehz025 7

Pharmaceutical manipulation of mitochondrial F0F1ATP synthase enables imaging and protection of myocardial ischemia/reperfusion injury through stressinduced selective enrichment

Squalene is oxidized by squalene monooxygenase (SQLE) to 2,3-epoxysqualene, which is cyclized to lanosterol by lanosterol synthase (LSS) ( Figure 1B )