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In REDEFINE 1 , a 68-week, Phase 3a, multicenter, double-blind, placebo- and active-controlled trial, 3,417 adults with overweight or obesity but without diabetes were randomized to CagriSema (cagrilintide 2.4 mg + semaglutide 2.4 mg), semaglutide 2.4 mg, cagrilintide 2.4 mg, or placebo

Localized redness or irritation may occur at the subcutaneous injection site

Form of Vitamin B12: The type of vitamin B12 used also plays a role

3 ml Syringe : While it also provides precise measurement, it is more suited for larger doses where exact small increments are less critical

This result is improved glucose clearance from the blood, which supports energy metabolism and reduces fat storage [6]