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The reduction in A plaques in the hippocampus and cortex was significant (25.6% and 31.5%, respectively when compared to control, see Fig

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By measuring various biomarkers in brain tissue samples including GABA, glutamate, KCC2, KNCC1, Gamma-Aminobutyric Acid Receptor Subunit Alpha-5 (GABRA5), EAAT2, vitamin D3 (VD3) and several oxidative stress biomarkers