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Additionally, these mice exhibited reduced MMP and increased ROS levels in their oocytes, indicating mitochondrial dysfunction and oxidative stress imbalance

Transepithelial Zn transport in the serosal-to-mucosal direction is thought to be primarily mediated by ZnT5, ZnT10, ZIP5, and ZIP14

short-term ambient excursions during transit do not measurably affect potency

Oxidative stress occurs when the production of ROS or RNS exceeds the antioxidant capacity of the cells, resulting in structural damage and oxidative modifications to proteins, lipids, and nucleic acids

Based on these premises, antioxidant treatments have been extensively used to potentially improve sperm parameters and increase the likelihood of conception