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Description

Iron within cells catalyzes ROS production via oxidase enzymes and lipoxygenase, and excess ROS triggers oxidative stress, activating caspases that cleave ferritin, resulting in its degradation [131]

Replenishing the skins collagen supply helps reinforce the dermal matrix, giving the skin the support it needs to stay firm and lifted

5-year graft survival was lower in Black recipients from Black donors and White recipients from Black donors compared to White recipients from White donors

MacArthur et al., 2024

[19] identified ring finger protein 217 as a novel E3 ligase mediating the degradation of ferroportin (FPN), which controls iron output alone or together with hepcidin