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Without these nutrients, your body may not metabolize fat as well as it could, leading to metabolic dysfunction and weight gain

Also, baseline TSH levels were higher and FT4 levels significantly lower (both indicating below optimal thyroid function) in the winter than in the summer among those who did not supplement with any vitamin D

Administered intravenously or intramuscularly, Methotrexate requires careful dosing and monitoring to mitigate potential side effects, including liver toxicity and bone marrow suppression, ensuring safe and effective treatment

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doi: 10.1186/s40104-025-01159-z 13