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Oxidation of methionine and acetylation of the protein N-terminus were selected for variable modifications, whereas carbamidomethylation of cysteines were chosen for fixed modification

doi:10.1038/sj.embor.7400036

National institute of environmental health sciences

Consistently, metabolites from the one-carbon pathway were lower in TCN2-KO cells than in TCN2-WT cells ( Figures 5D, E ), suggesting impaired folate one-carbon metabolism ( Figure 5F )

Researchers used NMDA receptor antagonists (APV), GABA receptor antagonists (BIC), and AMPA/KA receptor antagonists (DNQX) in order to pharmacologically isolate and observe evoked currents