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However, most of these trials lasted only a few weeks, included a small number of participants, and were not of the highest scientific quality

No cytotoxic effects were observed at concentrations used for stimulating collagen synthesis, antioxidant defense, and tissue repair

Effects of cellular cholesterol loading on macrophage foam cell lysosome acidification

Cancer 58 , 400406 (1994)

It also impairs endothelial tube formation in vitro, decreases HIF-1 stabilization and nuclear localization under hypoxic conditions, and inhibits MMP-2 and MMP-9 activity