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It possesses antioxidant, anti-inflammatory, and regenerative properties, improves circulation, supports stem cell functions, and promotes nerve outgrown and synthesis of neurotrophic factors

NAD+ enhances cellular resistance to oxidative stress by increasing -GCL, a key enzyme for glutathione synthesis

Side effects appear to be infrequent and mild in most reported cases, and may include: Temporary injection site reactions (with subcutaneous administration) Mild headache in some individuals Vivid dreams often considered a sign of enhanced REM sleep activity Occasional mild gastrointestinal discomfort DSIP does not appear to suppress respiratory function or cause the cognitive impairment sometimes associated with sedative-hypnotic drugs

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doi: 10.1016/j.tibs.2009.10.006, 23 Bouzier-SoreA