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However, conventional oral exogenous anti-inflammatory medicine includes glucocorticoids, nonsteroidal anti-inflammatory drugs (NSAIDs), which are unable to penetrate the joint space [119, 120]

doi: 10.1007/s00425-008-0820-3

Finally, if you've read the first edition and are worried this is a rerun with a new theme song, fret not

Additionally, we delineate that osthole reduces serum sphingosine-1-phosphate (S1P) to reduce pulmonary arterial pressure [7], and inhibits decadienyl-l-carnitine(C10:2) overaccumulation to alleviate PVR in PH rats[5]