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Antidotes for zinc intoxication in mice

Clinical VitC monotherapy studies Clinical monotherapy studies administering high-dose VitC in patients with various types of advanced malignancies report this therapy to be safe, showing no significant toxicity at doses of up to 3 g/kg [13] (Table 2)

Also, NCOA4-mediated ferritin degradation was reported in the brains of aging mice [330]

Studies in CD73 knock-out mice have demonstrated an increased expression of pro-inflammatory genes in LN LECs, leading to heightened recruitment of inflammatory DCs upon immunological challenge (120, 121)