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Inflammatory markers, such as IL-8 and TNF-, showed a marked decrease, while organ function indicators, including SOFA and APACHE II scores, significantly improved

Chang X, Zhu Y, Shi C, Stewart AK

There is a great deal of evidence that a major pathogenic role in oxidative stress is played by transition metals, such as iron, copper and zinc, which catalyzes oxidation reactions also in the brain and their imbalance was frequently detected in brain tissue of AD patients thereby representing an interesting therapeutic target in AD treatment (Gutteridge, 1994