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doi: 10.1161/01.atv.0000125703.20434.4d 72 XiaJYHollandWLKusminskiCMSunKSharmaAXPearsonMJet al

PloS One 8, e63388

It features an Arg3 substitution and an N-terminal extension that researchers study for altered receptor binding and reduced interaction with IGF binding proteins