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While universal vaccination may not be feasible given near-ubiquitous childhood infection, targeted immunization of high-risk individuals identified by HLA haplotyping (A2-B46 carriers in Northeastern India) as well as polymorphisms in detoxification and DNA-repair genes such as GSTM1, GSTT1, and XRCC1, particularly in Asian population remains a conceptually compelling preventive strategy that requires evaluation

Anxiety is a secondary concern

Glutathione intramuscular injections involves the direct delivery of glutathionea powerful antioxidantinto the muscle tissue for absorption into the bloodstream

This can lead to temporary flushing due to pH conversion

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