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Neurotoxicology 37:9399 Wegrzynowicz M, Hilgier W, Dybel A, Oja SS, Saransaari P, Albrecht J (2007) Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake

However, in the Site 2 pocket of C

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This phosphorylation recruits SH2 domain-containing phosphatases, specifically SHP-1 and SHP-2, which dephosphorylate key signaling molecules downstream of the TCR, leading to attenuation of T cell activation