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Description

NAD + homeostasis in health and disease

G., Meadows, G

doi:10.5301/jva.5000511

The longer isoform alone is known to act as a Rab GEF or Rab activating protein for Rab5 and Rac1GTPases, and it functions in endocytic mechanisms, endosomal dynamics, and micropinocytosis (Topp et al., 2004