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Next, we introduced multiple mutations in HGF, including point mutations (W321R, E336R, E361R, R373E, and Y376A), double mutation (W321R/Y376A), and triple mutation (W321R/E361R/Y376A), designed to weaken the interface III

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One study showed that patients with high blood pressure had reduced erythrocyte superoxide dismutase and increased oxidative stress relative to healthy people

Bunn concluded that folic acid and vitamin B12 supplementation significantly reduces the number of episodes of grade 4 hematologic or grade 3-4 non-hematologic toxicity associated with pemetrexed disodium use