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May 01, 2026 | Recovery A patient I had operated on three weeks earlier sat down across the desk, looked in the hand mirror she had brought, and asked the question I get more than any other at the two week visit

Chronic ketamine exposure in rodent models (50 mg/kg daily for 8 weeks) leads to significant activation of microglial cells and elevated expression of proinflammatory cytokines, such as IL-6 and IL-1, which correlate with hippocampal neuronal damage (Yin et al., 2022)