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IGF-1R is an important component of the signaling pathway in Graves ophthalmopathy, and downstream signaling of IGF-1 and IGF-1R plays a role in many immune-related diseases, possibly leading to disease occurrence through changes in immune phenotype and protein synthesis

In addition, PD target levels were determined based on preclinical data to allow an assessment of the relevance of the administered doses in terms of target inhibition during the Phase I clinical study and to determine the RP2D

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It also contains glutathione, a powerful antioxidant that is believed to have skin brightening and anti-aging benefits