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OBrien PD, Hinder LM, Callaghan BC, Feldman EL (2017) Neurological consequences of obesity

L-carnitine also has a secondary function of helping remove some waste products from the cells to prevent them from accumulating and causing problems.

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By further stimulating glucose uptake, suppressing the release of fatty acids from adipose tissue, and promoting fat and glycogen production, hyperinsulinemia following carbohydrate intake induces a vicious cycle that offers an explanation for why average BMI in many countries increased in the late 20th century as public health guidelines recommended replacement of dietary fat with carbohydrates, and consumption of high-glycemic-load foods increased substantially [51]

Patients specifically interested in NAD can read our dedicated guide to NAD IV therapy in Miami, which covers that protocol separately, including who it may suit and how the evidence is currently framed