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Free Radical Biol Med 120:S32 Starace AK, Black BA, Lee DD, Palmiotti EC, Orton KA, Michener WE, ten Dam J, Watson MJ, Beckham GT, Magrini KA (2017) Characterization and catalytic upgrading of aqueous stream carbon from catalytic fast pyrolysis of biomass

While enhanced alcohol metabolism may seem protective, elevated CYP2E1 accelerates ethanol oxidation, resulting in higher acetaldehyde production and excessive reactive oxygen species (ROS) generation, including hydroxyethyl radicals, superoxide anions, and hydroxyl radicals [27, 28]