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Description

GSNO solutions at 0.2 M with or without 0.2 M CD in 0.1 M phosphate buffer at pH 7.4 were prepared separately

Lets talk about the functions

Preclinical findings suggest that anti-PD-1/PD-L1 therapy can shift macrophage polarization from M2 to M1, transforming the immunosuppressive microenvironment into a pro-inflammatory state and ultimately prolonging survival in GBM-afflicted mice [508]