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Isoproterenol hydrochloride (Sigma-Aldrich) was dissolved in PBS and added in culture medium at a final concentration of 10 M and maintained throughout the experiment

Naiki T, Naiki-Ito A, Asamoto M, et al

Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion