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doi: 10.1159/000046904 87 Sagrillo-FagundesLAssuno SalustianoEMYenPWSolimanAVaillancourtC

Summaries of immunotherapies for T1D

Most prevalent are dry skin, eyes, nose and lips

Mechanistically, impaired iron exporte.g., zinc-mediated inhibition of amyloid precursor protein (APP) ferroxidase activityprovides a route to local iron accumulation (Duce et al., 2010), while familial AD presenilin mutations confer selective vulnerability to ferroptosis in human neuronal models (Greenough et al., 2022)