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Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): a phase 3, double-blind randomised trial

Patients should stop tirzepatide and seek immediate medical care if they experience severe, persistent abdominal pain (which may indicate pancreatitis), symptoms of gallbladder disease (right upper quadrant pain, fever, jaundice), persistent vomiting leading to dehydration (which may cause acute kidney injury), or signs of severe allergic reaction

Many patients report significant energy improvements and reduced fatigue

Designing circRNA-LNP vaccines to optimize self-adjuvant effects, improve circularization efficiency, and refine fragment length remains a key step for maximum efficacy (Chen et al., 2023)

This demonstrate that the models predictions of primaquine concentrations in breastfed infants is close to the actual true values with an absolute maximum error of 1.82 ng/mL (LLOQ)