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Recently, the MiOXSYS system has be proposed as a standardized assessment of seminal oxidative stress due to its ease of use, cost effectiveness, and reproducibility, as well as proposed evidence based clinical guidelines [150, 151]

Larger needles cause more tissue displacement and tend to produce more discomfort

NF-E2-related factor-2 (Nrf2) is a transactivator of genes that contain an antioxidant response element in their promoter

Mice were euthanized at humane endpoints (i.e., when the tumor size exceeded a total of 20 mm in length, when ulceration occurred, or when weight loss exceeded 20%)