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Macrophage or dendritic cell-derived IL-12 drives the expression of IFN in nave T cell, and both IL-12 and IFN upregulate the expression of transcription factor T-bet, which is responsible for differentiation of nave T cells into Th1 cell, as illustrated in Supplementary Figure 2B (70, 72)

For the Tau subclass, we found that Pav_sc0000164.1_g200.1.br ( PavGST56 ) and Pav_sc0011895.1_g020.1 .mk ( PavGST67 ) were the most highly expressed in all four treatments as compared to control while Pav_sc0002136.1_g320.1.mk ( PavGST14 ), Pav_sc0001708.1_g040.1.mk ( PavGST19 ) and Pav_sc0000207.1_g720.1.mk ( PavGST4 ) showed mild positive expression pattern as compared to untreated control

Miller AH, Raison CL

Pennsylvania Student Sustainability Symposium Location: Dickinson College Edwin Jordan Padilla Dickinson FarmData Date: March 21, 2014 Event: 2014 Pennsylvania Environmental Resource Consortium