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The probability of finding an unrelated donor (UD) with 9/10 or 10/10 HLA-matches (HLA-A, -B, -C, DRB1 and -DQB1) on the basis of high-resolution typing exceeds 70% for patients of European ancestry [96], but this likelihood depends on ethnicity [97]

In an experimental rodent model, Carlson et al

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Additionally, the S/T-3A mutation 37 , which disables serine/threonine phosphorylation sites at residues 356, 361 and 375 of XKR8, but not the 2DA mutants, enabled XKR8 KO HL-60 cells to expose PS in response to apoptosis induced by doxorubicin and NET induction by PMA, thereby restored the NET formation (Fig

These goals were periodically reviewed with the client and adjustments made as necessary