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doi: 10.1038/leu.2015.123 41 FedelePLWillisSNLiaoYLowMSRautelaJSegalDHet al

The NAD + -CD38-cADPR-Ca 2+ axis, based on the ectoenzyme activity of CD38, regulates the tumor microenvironment by a series of reactions following Ca 2+ flux