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A cascade involving edema, an inflammatory response, ROS/reactive nitrogen species (RNS) production, glutamate-mediated toxic effects, neuronal apoptosis, ferroptosis, and glial scarring occurs after SCI [31,32,33]

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In this regard, oxidative stress is one of the factors that alter mitochondrial dynamics balance, mainly in the direction of fission

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In conclusion, we have developed and extensively characterised the NAPstar family, which are the first bona fide biosensors of the NADP redox state