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doi: 10.1016/S0304-3959(01)00363-3 196 PoruchynskyM

Takahashi, A., Ikarashi, Y., Ishimaru, H

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Research has explored whether NNMT inhibitions effects extend beyond direct enzyme activity to broader metabolic reprogramming, including observations of altered mitochondrial function, lipid oxidation, and gene expression in research models

FIGURE 7 4.4.1 Lipid peroxidation products MDA (often measured by TBARS), 4-HNE, 8-iso-PGF 2 , lipid hydroperoxides (LOOHs), and oxidized LDL (oxLDL)arise when polyunsaturated lipids are attacked by ROS