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Imaging studies revealed that 85 % had large-duct disease (moderate or advanced change pancreatitis by endoscopic pancreatography), with or without calculi , and 15 % had small-duct disease, usually identified by secretin-pancreozymin tests

In a French study by Chiche et al., among 103 patients treated with CPX-351, CR rate was 55%, with a median OS of 16.1 months

Phase I creates intermediate metabolites that can create a tremendous amount of oxidative stress in the body unless they are effectively conjugated in Phase II

Similar to previously reported studies [23], the severity of nasal discharge and facial swelling in the infected chickens was scored on the following scale: 0 for no clinical symptoms

doi: 10.1016/j.cell.2019.12.035