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Relevant researchers (Zhou et al., 2015) found that YGJ and its main component iYGJ can inhibit liver angiogenesis in cirrhotic mice by inhibiting the HIF-1/VEGF signaling pathway, and finally confirmed that its anti-angiogenesis effect is closely related to improving the liver hypoxic microenvironment

ROS-related anticancer mechanisms include mitochondrial dysfunction, p53-dependent apoptosis, iron-dependent ferroptosis, activation of endoplasmic reticulum stress, inhibition of growth signaling pathways (such as the epidermal growth factor pathway, EGF), among others

N-acetylcysteine (NAC) is a precursor to glutathione

doi: 10.1016/j.nbd.2025.106851 17 LiSYangDZhouXChenLLiuLLinRet al

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