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The guidelines state, However, pernicious anaemia in its true sense (that is, life-threatening anaemia) is now extremely rare because of developments in testing and treatment for, and greater awareness of, vitamin B 12 deficiency . In one sense, this statement is correct: the term pernicious anaemia, when taken literally, implies a severe, life-threatening form of anaemia, which is uncommon in modern practice due to improvements in testing and treatment, such severe manifestations are typically prevented, as the condition is more likely to be diagnosed earlier or treated with B 12

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Vitamin B12 Deficiency and the Nervous System: Beyond Metabolic DecompensationComparing Biological Models and Gaining New Insights into Molecular and Cellular Mechanisms

Acute fluid volume changes in men during three days of creatine supplementation

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