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Although cagrilintide-semaglutide produced greater weight loss than either monotherapy alone in REDEFINE 1, the study design does not permit a formal assessment of pharmacological additivity or synergy

Luo et al 150 used SLA to make bone defect repair scaffolds with a porous structure and high mechanical strength by combining ECM with PEGDA, which resulted in the upregulation of the expression of RNAs that regulate osteogenic differentiation and better repair of bone defects

quantified 4,405 proteins in murine hepatic organoids and observed differentiation-dependent upregulation of CYP450 enzymes, hepatic transporters, and other metabolic proteins, which parallels our observations in human iHLOs 14

Under the treatment-regimen estimand, reflecting real-world adherence conditions, the figures were 20.2% versus 23.6%

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