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R.SantiagoM.MachadoA.CanoJ

Glutathion ist ein Tripeptid, das im menschlichen Krper berwiegend in der Leber aus den drei Aminosuren Glutaminsure, Cystein und Glycin gebildet wird und gehrt zu den wichtigsten zellulren Antioxidantien

However, combinatorial regimens integrating these compounds with conventional chemotherapeutic agents not only potentiate natural product efficacy but also reverse chemoresistance via synergistic ROS-mediated mechanisms

The research was supported in part by the National Institute of General Medical Sciences (R35GM127045 awarded to S.L.S.), the NCIs Cancer Target Discovery and Development (CTD^2) Network (grant number U01CA217848 and U01CA272612 awarded to S.L.S.), and by the NIBR Scholars Program