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The immobilized template can be reused in the next IVT reaction at least six times

Copper ionophores Copper ionophores transport copper into the cells, leading to an increase in intracellular copper levels and subsequent cell death

Brain Res Bull 116:6772 Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, Sauve AA, Pasinetti GM (2006) Neuronal SIRT1 activation as a novel mechanism underlying the prevention of alzheimer disease amyloid neuropathology by calorie restriction

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