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Ten years ago I had a sudden onset of joint pain which prevented me from keeping up with my work

24 Compared with obstructive sleep apnea, central sleep apnea is much less common, occurring in less than 1% of adults

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Interestingly, the overexpression of the individual protein isoforms in vitro results in distinct transcriptional regulatory profiles, with only about 10% overlap ( in vitro transactivation activity of all translational isoforms, which is thought to be mediated by the absence of amino acids 197, leading to enhanced recruitment of co-activators to the AF-1 domain ( in vitro transcriptional regulatory activity

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