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The spectrophotometric detection limit for Tyr is 8 10 7 mol L 1

[1] [8] Key interactions to be aware of include: Insulin and insulin secretagogues (such as sulphonylureas): Concurrent use may increase the risk of hypoglycaemia, and dose adjustments may be necessary

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In Study JMCH, incidences of Grade 3 to 4 neutropenia (38% versus 23%), thrombocytopenia (9% versus 5%), febrile neutropenia (9% versus 0.6%), and neutropenic infection (6% versus 0) were higher in patients who received pemetrexed plus cisplatin without vitamin supplementation as compared to patients who were fully supplemented with folic acid and vitamin B 12 prior to and throughout pemetrexed plus cisplatin treatment

Sharma S, Mells JE, Fu PP, Saxena NK, Anania FA