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Metformin treatment (72 h) induced a significant increase in early and late apoptotic HCT116 cells, when compared to vehicle control ( Figures 3B, D )

Specifically, research shows that Bifidobacterium adolescentis is a high GABA producer.[ref] Lactobacillus brevis DPC6108 and Lactobacillus rhamnosus are also probiotic strains that produce GABA.[ref][ref] A 2024 double blind placebo controlled trial found that a probiotic formulation of Lactobacillus brevis and Lactiplantibacillus plantarum reduced symptoms of depression and improved mood, but did not affect stress levels

doi: 10.1038/bjc.2014.175

A mutation was identified in the gene encoding the forkhead transcription factor, Foxe3, in the dyl strain

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